Little Lab: Publications

  1. Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making. Hoy CW, de Hemptinne C, Wang SS, Harmer CJ, Apps MAJ, Husain M, Starr PA, Little S. Proceedings of the National Academy of Sciences. 2024 Jul 30;121(31). doi: 10.1073/pnas.2322869121.

  2. Neuropsychological and social predictors of participation in a deep brain stimulation study of Parkinson's disease and dystonia. Hahn A, Lazar AA, Cernera S, Little S, Wang SS, Starr PA, Racine CA. Deep Brain Stimulation. 2024 Jul 14. doi: 10.1016/j.jdbs.2024.07.002

  3. Interpretable video-based tracking and quantification of parkinsonism clinical motor states. Deng D, Ostrem JL, Nguyen V, Cummins DD, Sun J, Pathak A, Little S, Abbasi-Asl R. npj Parkinson's Disease. 2024 Jun 25;10(1):122. doi: 10.1038/s41531-024-00742-x.

  4. Motor network gamma oscillations in chronic home recordings predict dyskinesia in Parkinson’s disease. Olaru M, Cernera S, Hahn A, Wozny TA, Anso J, de Hemptinne C, Little S, Neumann WJ, Abbasi-Asl R, Starr PA. Brain. 2024 Jun;147(6):2038-2052. doi: 10.1093/brain/awae004.

  5. Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson’s disease. Cagle JN, de Araujo T, Johnson KA, Yu J, Fanty L, Sarmento FP, Little S, Okun MS, Wong JK, de Hemptinne C. Nature Communications. 2024 May 30;15(1):4602. doi: 10.1038/s41467-024-48732-0.

  6. Short term cardiovascular symptoms improvement after deep brain stimulation in patients with Parkinson's disease: a systematic review. Cucinotta F, Swinnen B, Makovac E, Hirschbichler S, Pereira E, Little S, Morgante F, Ricciardi L. Journal of Neurology. 2024 May 29;1-13. doi: 10.1007/s00415-024-12459-1.

  7. Generalized sleep decoding with basal ganglia signals in multiple movement disorders. Yin Z, Yu H, Yuan T, Smyth C, Anjum MF, Zhu G, Ma R, Xu Y, An Q, Gan Y, Merk T, Qin G, Xie H, Zhang N, Wang C, Jiang Y, Meng F, Yang A, Neumann WJ, Starr P, Little S, Li L, Zhang J. npj Digital Medicine. 2024 May 10;7(1):122. doi: 10.1038/s41746-024-01115-7.

  8. Multi-night cortico-basal recordings reveal mechanisms of NREM slow-wave suppression and spontaneous awakenings in Parkinson’s disease. Anjum MF, Smyth C, Zuzuárregui R, Dijk DJ, Starr PA, Denison T, Little S. Nature Communications. 2024 Feb 27;15(1):1793. doi: 10.1038/s41467-024-46002-7.

  9. Towards therapeutic electrophysiological neurofeedback in Parkinson's disease. Matzilevich EU, Daniel PL, Little S. Parkinsonism & Related Disorders. 2024 Jan 14;106010. doi: 10.1016/j.parkreldis.2023.106010.

  10. Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings. Ricciardi L, Apps M, Little S.NPJ Parkinsons Dis. 2023 Sep 21;9(1):136. doi: 10.1038/s41531-023-00567-0.PMID: 37735477 

  11. Using Neuroscientific and Clinical Context to Assess and Manage Changes in Core Personal Traits Caused by Deep Brain Stimulation. Hoy CW, Little SJ, Chiong W.AJOB Neurosci. 2023 Jul-Sep;14(3):310-312. doi: 10.1080/21507740.2023.2243873.PMID: 37682669 

  12.  Sub-harmonic entrainment of cortical gamma oscillations to deep brain stimulation in Parkinson's disease: Model based predictions and validation in three human subjects. Sermon JJ, Olaru M, Anso J, Cernera S, Little S, Shcherbakova M, Bogacz R, Starr PA, Denison T, Duchet B.Brain Stimul. 2023 Sep 6:S1935-861X(23)01902-2. doi: 10.1016/j.brs.2023.08.026. Online ahead of print.PMID: 37683763

  13. Using Neuroscientific and Clinical Context to Assess and Manage Changes in Core Personal Traits Caused by Deep Brain Stimulation. Hoy CW, Little SJ, Chiong W.AJOB Neurosci. 2023 Jul-Sep;14(3):310-312. doi: 10.1080/21507740.2023.2243873.PMID: 37682669

  14. Personalized chronic adaptive deep brain stimulation outperforms conventional stimulation in Parkinson's disease. Oehrn CR, Cernera S, Hammer LH, Shcherbakova M, Yao J, Hahn A, Wang S, Ostrem JL, Little S, Starr PA.medRxiv. 2023 Aug 8:2023.08.03.23293450. doi: 10.1101/2023.08.03.23293450. Preprint.PMID: 37649907

  15. Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson's disease. Smyth C, Anjum MF, Ravi S, Denison T, Starr P, Little S.Brain Stimul. 2023 Aug 9;16(5):1292-1296. doi: 10.1016/j.brs.2023.08.006. Online ahead of print.PMID: 37567463

  16. Bringing the Clinic Home: An At-Home Multi-Modal Data Collection Ecosystem to Support Adaptive Deep Brain Stimulation. Strandquist G, Frączek T, Dixon T, Ravi S, Bechtold R, Lawrence D, Zeng A, Gallant J, Little S, Herron J.J Vis Exp. 2023 Jul 14;(197). doi: 10.3791/65305.PMID: 37522736

  17. Adaptive Deep Brain Stimulation: From Experimental Evidence Toward Practical Implementation. Mov Disord. 2023 May 06. Neumann WJ, Gilron R, Little S, Tinkhauser G. PMID: 37148553.View in: PubMed   

  18. Cortico-Subthalamic Field Potentials Support Classification of the Natural Gait Cycle in Parkinson's Disease and Reveal Individualized Spectral Signatures. eNeuro. 2022 Nov-Dec; 9(6). Louie KH, Gilron R, Yaroshinsky MS, Morrison MA, Choi J, de Hemptinne C, Little S, Starr PA, Wang DD. PMID: 36270803; PMCID: PMC9663205.

  19. Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience. J Neural Eng. 2022 Mar 31; 19(2). Ansó J, Benjaber M, Parks B, Parker S, Oehrn CR, Petrucci M, Gilron R, Little S, Wilt R, Bronte-Stewart H, Gunduz A, Borton D, Starr PA, Denison T. PMID: 35234664; PMCID: PMC9095704.

    View in: PubMed   Mentions: Article has an altmetric score of 9

  20. Embedding digital chronotherapy into bioelectronic medicines. iScience. 2022 Apr 15; 25(4):104028. Fleming JE, Kremen V, Gilron R, Gregg NM, Zamora M, Dijk DJ, Starr PA, Worrell GA, Little S, Denison TJ. PMID: 35313697; PMCID: PMC8933700.

    View in: PubMed   Mentions: Article has an altmetric score of 5

  21. Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury. Front Hum Neurosci. 2022; 16:813387. Wong JK, Deuschl G, Wolke R, Bergman H, Muthuraman M, Groppa S, Sheth SA, Bronte-Stewart HM, Wilkins KB, Petrucci MN, Lambert E, Kehnemouyi Y, Starr PA, Little S, Anso J, Gilron R, Poree L, Kalamangalam GP, Worrell GA, Miller KJ, Schiff ND, Butson CR, Henderson JM, Judy JW, Ramirez-Zamora A, Foote KD, Silburn PA, Li L, Oyama G, Kamo H, Sekimoto S, Hattori N, Giordano JJ, DiEuliis D, Shook JR, Doughtery DD, Widge AS, Mayberg HS, Cha J, Choi K, Heisig S, Obatusin M, Opri E, Kaufman SB, Shirvalkar P, Rozell CJ, Alagapan S, Raike RS, Bokil H, Green D, Okun MS. PMID: 35308605; PMCID: PMC8931265.

    View in: PubMed   Mentions: Article has an altmetric score of 27

  22. Artifact Characterization and a Multipurpose Template-Based Offline Removal Solution for a Sensing-Enabled Deep Brain Stimulation Device. Stereotact Funct Neurosurg. 2022; 100(3):168-183. Hammer LH, Kochanski RB, Starr PA, Little S. PMID: 35130555; PMCID: PMC9064887.

    View in: PubMed   Mentions: Article has an altmetric score of 1

  23. Rapid Dynamic Naturalistic Monitoring of Bradykinesia in Parkinson's Disease Using a Wrist-Worn Accelerometer. Sensors (Basel). 2021 Nov 26; 21(23). Habets JGV, Herff C, Kubben PL, Kuijf ML, Temel Y, Evers LJW, Bloem BR, Starr PA, Gilron R, Little S. PMID: 34883886; PMCID: PMC8659489.

    View in: PubMed   Mentions: Article has an altmetric score of 4

  24. Prefrontal Physiomarkers of Anxiety and Depression in Parkinson's Disease. Front Neurosci. 2021; 15:748165. de Hemptinne C, Chen W, Racine CA, Seritan AL, Miller AM, Yaroshinsky MS, Wang SS, Gilron R, Little S, Bledsoe I, San Luciano M, Katz M, Chang EF, Dawes HE, Ostrem JL, Starr PA. PMID: 34744613; PMCID: PMC8568318.

    View in: PubMed   Mentions: Article has an altmetric score of 13

  25. Sleep-Aware Adaptive Deep Brain Stimulation Control: Chronic Use at Home With Dual Independent Linear Discriminate Detectors. Front Neurosci. 2021; 15:732499. Gilron R, Little S, Wilt R, Perrone R, Anso J, Starr PA. PMID: 34733132; PMCID: PMC8558614.

    View in: PubMed   Mentions: Article has an altmetric score of 11

  26. Corrigendum: Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:765150. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Hu W, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 34658825; PMCID: PMC8517517.

    View in: PubMed   Mentions: Article has an altmetric score of 2

  27. The sensitivity of ECG contamination to surgical implantation site in brain computer interfaces. Brain Stimul. 2021 Sep-Oct; 14(5):1301-1306. Neumann WJ, Memarian Sorkhabi M, Benjaber M, Feldmann LK, Saryyeva A, Krauss JK, Contarino MF, Sieger T, Jech R, Tinkhauser G, Pollo C, Palmisano C, Isaias IU, Cummins DD, Little SJ, Starr PA, Kokkinos V, Gerd-Helge S, Herrington T, Brown P, Richardson RM, Kühn AA, Denison T. PMID: 34428554; PMCID: PMC8460992.

    View in: PubMed   Mentions: Article has an altmetric score of 20   Fields: Bra
       

  28. Laminar dynamics of high amplitude beta bursts in human motor cortex. Neuroimage. 2021 11 15; 242:118479. Bonaiuto JJ, Little S, Neymotin SA, Jones SR, Barnes GR, Bestmann S. PMID: 34407440; PMCID: PMC8463839.

    View in: PubMed   Mentions: Article has an altmetric score of 21   Fields: Dia
       

  29. Chronic Sensing of Subthalamic Local Field Potentials: Comparison of First and Second Generation Implantable Bidirectional Systems Within a Single Subject. Front Neurosci. 2021; 15:725797. Cummins DD, Kochanski RB, Gilron R, Swann NC, Little S, Hammer LH, Starr PA. PMID: 34447294; PMCID: PMC8382799.

    View in: PubMed

  30. Embedded adaptive deep brain stimulation for cervical dystonia controlled by motor cortex theta oscillations. Exp Neurol. 2021 11; 345:113825. Johnson V, Wilt R, Gilron R, Anso J, Perrone R, Beudel M, Piña-Fuentes D, Saal J, Ostrem JL, Bledsoe I, Starr P, Little S. PMID: 34331900.

    View in: PubMed   Mentions: 1  Article has an altmetric score of 11   Fields: Neu
       

  31. Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System. Front Hum Neurosci. 2021; 15:714256. Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA. PMID: 34322004; PMCID: PMC8312257.

    View in: PubMed   Mentions: 1

  32. Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease. Nat Biotechnol. 2021 09; 39(9):1078-1085. Gilron R, Little S, Perrone R, Wilt R, de Hemptinne C, Yaroshinsky MS, Racine CA, Wang SS, Ostrem JL, Larson PS, Wang DD, Galifianakis NB, Bledsoe IO, San Luciano M, Dawes HE, Worrell GA, Kremen V, Borton DA, Denison T, Starr PA. PMID: 33941932; PMCID: PMC8434942.

    View in: PubMed   Mentions: 7  Article has an altmetric score of 371   Fields: Bio Translation:Humans

  33. Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:644593. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS, Hu W. PMID: 33953663; PMCID: PMC8092047.

    View in: PubMed   Mentions: 3  Article has an altmetric score of 173

  34. The Neurophysiology of Sleep in Parkinson's Disease. Mov Disord. 2021 07; 36(7):1526-1542. Zahed H, Zuzuarregui JRP, Gilron R, Denison T, Starr PA, Little S. PMID: 33826171.

    View in: PubMed   Mentions: Article has an altmetric score of 21   Fields: Neu Translation:Humans

  35. A space-time continuum in DBS: structural and functional advances in Parkinson's disease. Brain. 2021 03 03; 144(2):357-359. Starr P, Little S. PMID: 33693692.

    View in: PubMed   Mentions: Article has an altmetric score of 22   Fields: BraNeu Translation:Humans

  36. Acute effects of adaptive Deep Brain Stimulation in Parkinson's disease. Brain Stimul. 2020 Nov - Dec; 13(6):1507-1516. Piña-Fuentes D, van Dijk JMC, van Zijl JC, Moes HR, van Laar T, Oterdoom DLM, Little S, Brown P, Beudel M. PMID: 32738409; PMCID: PMC7116216.

    View in: PubMed   Mentions: 3  Article has an altmetric score of 23   Fields: Bra Translation:Humans

  37. Proceedings of the Seventh Annual Deep Brain Stimulation Think Tank: Advances in Neurophysiology, Adaptive DBS, Virtual Reality, Neuroethics and Technology. Front Hum Neurosci. 2020; 14:54. Ramirez-Zamora A, Giordano J, Gunduz A, Alcantara J, Cagle JN, Cernera S, Difuntorum P, Eisinger RS, Gomez J, Long S, Parks B, Wong JK, Chiu S, Patel B, Grill WM, Walker HC, Little SJ, Gilron R, Tinkhauser G, Thevathasan W, Sinclair NC, Lozano AM, Foltynie T, Fasano A, Sheth SA, Scangos K, Sanger TD, Miller J, Brumback AC, Rajasethupathy P, McIntyre C, Schlachter L, Suthana N, Kubu C, Sankary LR, Herrera-Ferrá K, Goetz S, Cheeran B, Steinke GK, Hess C, Almeida L, Deeb W, Foote KD, Okun MS. PMID: 32292333; PMCID: PMC7134196.

    View in: PubMed   Mentions: 6  Article has an altmetric score of 20

  38. Prefrontal-Subthalamic Hyperdirect Pathway Modulates Movement Inhibition in Humans. Neuron. 2020 05 20; 106(4):579-588.e3. Chen W, de Hemptinne C, Miller AM, Leibbrand M, Little SJ, Lim DA, Larson PS, Starr PA. PMID: 32155442; PMCID: PMC7274135.

    View in: PubMed   Mentions: 25  Article has an altmetric score of 17   Fields: Neu Translation:Humans

  39. Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease. Mov Disord. 2020 04; 35(4):555-561. Little S, Brown P. PMID: 32039501; PMCID: PMC7166127.

    View in: PubMed   Mentions: 9  Article has an altmetric score of 1   Fields: Neu Translation:Humans

  40. Human motor cortical beta bursts relate to movement planning and response errors. PLoS Biol. 2019 10; 17(10):e3000479. Little S, Bonaiuto J, Barnes G, Bestmann S. PMID: 31584933; PMCID: PMC6795457.

    View in: PubMed   Mentions: 15  Article has an altmetric score of 25   Fields: Bio Translation:Humans

  41. Adaptive deep brain stimulation as advanced Parkinson's disease treatment (ADAPT study): protocol for a pseudo-randomised clinical study. BMJ Open. 2019 06 14; 9(6):e029652. Piña-Fuentes D, Beudel M, Little S, Brown P, Oterdoom DLM, van Dijk JMC. PMID: 31201193; PMCID: PMC6575861.

    View in: PubMed   Mentions: 5  Article has an altmetric score of 4   Fields: Med Translation:HumansCT

  42. Phase-Dependent Suppression of Beta Oscillations in Parkinson's Disease Patients. J Neurosci. 2019 02 06; 39(6):1119-1134. Holt AB, Kormann E, Gulberti A, Pötter-Nerger M, McNamara CG, Cagnan H, Baaske MK, Little S, Köppen JA, Buhmann C, Westphal M, Gerloff C, Engel AK, Brown P, Hamel W, Moll CKE, Sharott A. PMID: 30552179; PMCID: PMC6363933.

    View in: PubMed   Mentions: 19  Article has an altmetric score of 29   Fields: Neu Translation:HumansCells

  43. The characteristics of pallidal low-frequency and beta bursts could help implementing adaptive brain stimulation in the parkinsonian and dystonic internal globus pallidus. Neurobiol Dis. 2019 01; 121:47-57. Piña-Fuentes D, van Zijl JC, van Dijk JMC, Little S, Tinkhauser G, Oterdoom DLM, Tijssen MAJ, Beudel M. PMID: 30227227.

    View in: PubMed   Mentions: 13  Article has an altmetric score of 4   Fields: Neu Translation:Humans

  44. Toward adaptive deep brain stimulation for dystonia. Neurosurg Focus. 2018 08; 45(2):E3. Piña-Fuentes D, Beudel M, Little S, van Zijl J, Elting JW, Oterdoom DLM, van Egmond ME, van Dijk JMC, Tijssen MAJ. PMID: 30064317.

    View in: PubMed   Mentions: 4  Article has an altmetric score of 9   Fields: Neu Translation:Humans

  45. Parkinsonian Tremor Detection from Subthalamic Nucleus Local Field Potentials for Closed-Loop Deep Brain Stimulation. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:2320-2324. Shah SA, Tinkhauser G, Chen CC, Little S, Brown P. PMID: 30440871; PMCID: PMC6277049.

    View in: PubMed   Mentions: 7  Article has an altmetric score of 1Translation:Humans

  46. Alternating Modulation of Subthalamic Nucleus Beta Oscillations during Stepping. J Neurosci. 2018 05 30; 38(22):5111-5121. Fischer P, Chen CC, Chang YJ, Yeh CH, Pogosyan A, Herz DM, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hasegawa H, Samuel M, Ashkan K, Brown P, Tan H. PMID: 29760182; PMCID: PMC5977446.

    View in: PubMed   Mentions: 17  Article has an altmetric score of 61   Fields: Neu Translation:Humans

  47. Mechanisms Underlying Decision-Making as Revealed by Deep-Brain Stimulation in Patients with Parkinson's Disease. Curr Biol. 2018 04 23; 28(8):1169-1178.e6. Herz DM, Little S, Pedrosa DJ, Tinkhauser G, Cheeran B, Foltynie T, Bogacz R, Brown P. PMID: 29606416; PMCID: PMC5912902.

    View in: PubMed   Mentions: 19  Article has an altmetric score of 11   Fields: Bio Translation:Humans

  48. Adaptive Brain Stimulation for Movement Disorders. Prog Neurol Surg. 2018; 33:230-242. Beudel M, Cagnan H, Little S. PMID: 29332087.

    View in: PubMed   Mentions: 1  Article has an altmetric score of 1   Fields: Neu Translation:HumansAnimals

  49. Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition. Elife. 2017 07 25; 6. Fischer P, Pogosyan A, Herz DM, Cheeran B, Green AL, Fitzgerald J, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Brown P, Tan H. PMID: 28742498; PMCID: PMC5526662.

    View in: PubMed   Mentions: 14  Article has an altmetric score of 2   Fields: Bio Translation:Humans

  50. Adaptive DBS in a Parkinson's patient with chronically implanted DBS: A proof of principle. Mov Disord. 2017 08; 32(8):1253-1254. Piña-Fuentes D, Little S, Oterdoom M, Neal S, Pogosyan A, Tijssen MAJ, van Laar T, Brown P, van Dijk JMC, Beudel M. PMID: 28589687; PMCID: PMC5580798.

    View in: PubMed   Mentions: 20   Fields: Neu Translation:Humans

  51. The modulatory effect of adaptive deep brain stimulation on beta bursts in Parkinson's disease. Brain. 2017 Apr 01; 140(4):1053-1067. Tinkhauser G, Pogosyan A, Little S, Beudel M, Herz DM, Tan H, Brown P. PMID: 28334851; PMCID: PMC5382944.

    View in: PubMed   Mentions: 93  Article has an altmetric score of 13   Fields: BraNeu Translation:Humans

  52. Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force. Exp Neurol. 2017 07; 293:53-61. Fischer P, Pogosyan A, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Samuel M, Ashkan K, Brown P, Tan H. PMID: 28342747; PMCID: PMC5429975.

    View in: PubMed   Mentions: 8  Article has an altmetric score of 2   Fields: Neu Translation:Humans

  53. Distinct mechanisms mediate speed-accuracy adjustments in cortico-subthalamic networks. Elife. 2017 01 31; 6. Herz DM, Tan H, Brittain JS, Fischer P, Cheeran B, Green AL, FitzGerald J, Aziz TZ, Ashkan K, Little S, Foltynie T, Limousin P, Zrinzo L, Bogacz R, Brown P. PMID: 28137358; PMCID: PMC5287713.

    View in: PubMed   Mentions: 17  Article has an altmetric score of 108   Fields: Bio Translation:Humans

  54. Stimulating at the right time: phase-specific deep brain stimulation. Brain. 2017 01; 140(1):132-145. Cagnan H, Pedrosa D, Little S, Pogosyan A, Cheeran B, Aziz T, Green A, Fitzgerald J, Foltynie T, Limousin P, Zrinzo L, Hariz M, Friston KJ, Denison T, Brown P. PMID: 28007997; PMCID: PMC5226063.

    View in: PubMed   Mentions: 56  Article has an altmetric score of 35   Fields: BraNeu Translation:Humans

  55. Spectral power changes prior to psychogenic non-epileptic seizures: a pilot study. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):190-192. Meppelink AM, Pareés I, Beudel M, Little S, Yogarajah M, Sisodiya S, Edwards MJ. PMID: 27789542.

    View in: PubMed   Mentions: 3  Article has an altmetric score of 2   Fields: NeuNeuPsy Translation:Humans

  56. Adaptive deep brain stimulation for Parkinson's disease demonstrates reduced speech side effects compared to conventional stimulation in the acute setting. J Neurol Neurosurg Psychiatry. 2016 12; 87(12):1388-1389. Little S, Tripoliti E, Beudel M, Pogosyan A, Cagnan H, Herz D, Bestmann S, Aziz T, Cheeran B, Zrinzo L, Hariz M, Hyam J, Limousin P, Foltynie T, Brown P. PMID: 27530809; PMCID: PMC5136720.

    View in: PubMed   Mentions: 55  Article has an altmetric score of 13   Fields: NeuNeuPsy Translation:Humans

  57. Decisions Made with Less Evidence Involve Higher Levels of Corticosubthalamic Nucleus Theta Band Synchrony. J Cogn Neurosci. 2016 06; 28(6):811-25. Zavala B, Tan H, Little S, Ashkan K, Green AL, Aziz T, Foltynie T, Zrinzo L, Zaghloul K, Brown P. PMID: 26845109; PMCID: PMC5111088.

    View in: PubMed   Mentions: 9  Article has an altmetric score of 2   Fields: Neu Translation:Humans

  58. Bilateral adaptive deep brain stimulation is effective in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2016 07; 87(7):717-21. Little S, Beudel M, Zrinzo L, Foltynie T, Limousin P, Hariz M, Neal S, Cheeran B, Cagnan H, Gratwicke J, Aziz TZ, Pogosyan A, Brown P. PMID: 26424898; PMCID: PMC4941128.

    View in: PubMed   Mentions: 68  Article has an altmetric score of 29   Fields: NeuNeuPsy Translation:Humans

  59. Tremor Reduction by Deep Brain Stimulation Is Associated With Gamma Power Suppression in Parkinson's Disease. Neuromodulation. 2015 Jul; 18(5):349-54. Beudel M, Little S, Pogosyan A, Ashkan K, Foltynie T, Limousin P, Zrinzo L, Hariz M, Bogdanovic M, Cheeran B, Green AL, Aziz T, Thevathasan W, Brown P. PMID: 25879998; PMCID: PMC4829100.

    View in: PubMed   Mentions: 19  Article has an altmetric score of 11   Fields: Neu Translation:Humans

  60. Excessive neural synchrony in Machado-Joseph disease responsive to subthalamic nucleus stimulation. Mov Disord. 2015 Mar; 30(3):437-8. Anzak A, Little S, Hulse N, Andrews T, Brown P, Samuel M, Ashkan K. PMID: 25689061.

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  61. The nature of tremor circuits in parkinsonian and essential tremor. Brain. 2014 Dec; 137(Pt 12):3223-34. Cagnan H, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Cheeran B, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 25200741; PMCID: PMC4240284.

    View in: PubMed   Mentions: 25  Article has an altmetric score of 18   Fields: BraNeu Translation:Humans

  62. Controlling Parkinson's disease with adaptive deep brain stimulation. J Vis Exp. 2014 Jul 16; (89). Little S, Pogosyan A, Neal S, Zrinzo L, Hariz M, Foltynie T, Limousin P, Brown P. PMID: 25077449; PMCID: PMC4217393.

    View in: PubMed   Mentions: 8  Article has an altmetric score of 1   Fields: BioMed Translation:Humans

  63. Midline frontal cortex low-frequency activity drives subthalamic nucleus oscillations during conflict. J Neurosci. 2014 May 21; 34(21):7322-33. Zavala BA, Tan H, Little S, Ashkan K, Hariz M, Foltynie T, Zrinzo L, Zaghloul KA, Brown P. PMID: 24849364; PMCID: PMC4028502.

    View in: PubMed   Mentions: 50  Article has an altmetric score of 10   Fields: Neu Translation:Humans

  64. The functional role of beta oscillations in Parkinson's disease. Parkinsonism Relat Disord. 2014 Jan; 20 Suppl 1:S44-8. Little S, Brown P. PMID: 24262186.

    View in: PubMed   Mentions: 67  Article has an altmetric score of 6   Fields: Neu Translation:Humans

  65. Bilateral functional connectivity of the basal ganglia in patients with Parkinson's disease and its modulation by dopaminergic treatment. PLoS One. 2013; 8(12):e82762. Little S, Tan H, Anzak A, Pogosyan A, Kühn A, Brown P. PMID: 24376574; PMCID: PMC3869733.

    View in: PubMed   Mentions: 23   Fields: MedSci Translation:Humans

  66. Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation. Brain. 2013 Oct; 136(Pt 10):3062-75. Cagnan H, Brittain JS, Little S, Foltynie T, Limousin P, Zrinzo L, Hariz M, Joint C, Fitzgerald J, Green AL, Aziz T, Brown P. PMID: 24038075; PMCID: PMC3784287.

    View in: PubMed   Mentions: 36  Article has an altmetric score of 9   Fields: BraNeu Translation:Humans

  67. Adaptive deep brain stimulation in advanced Parkinson disease. Ann Neurol. 2013 Sep; 74(3):449-57. Little S, Pogosyan A, Neal S, Zavala B, Zrinzo L, Hariz M, Foltynie T, Limousin P, Ashkan K, FitzGerald J, Green AL, Aziz TZ, Brown P. PMID: 23852650; PMCID: PMC3886292.

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  68. What brain signals are suitable for feedback control of deep brain stimulation in Parkinson's disease? Ann N Y Acad Sci. 2012 Aug; 1265:9-24. Little S, Brown P. PMID: 22830645; PMCID: PMC3495297.

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  69. A torque-based method demonstrates increased rigidity in Parkinson's disease during low-frequency stimulation. Exp Brain Res. 2012 Jun; 219(4):499-506. Little S, Joundi RA, Tan H, Pogosyan A, Forrow B, Joint C, Green AL, Aziz TZ, Brown P. PMID: 22580572; PMCID: PMC3366185.

    View in: PubMed   Mentions: 6  Article has an altmetric score of 4   Fields: Bra Translation:Humans